The integration of artificial intelligence (AI) into medical imaging has guided an era of transformation in healthcare. This
paper presents the research activities that a multidisciplinary research group within the Signals and Images Lab of the
Institute of Information Science and Technologies of the National Research Council of Italy is carrying out to explore the great
potential of AI in medical imaging. From the convolutional neural network-based segmentation of Covid-19 lung patterns to
the radiomic signature for benign/malignant breast nodule discrimination, to the automatic grading of prostate cancer, this
work highlights the paradigm shift that AI has brought to medical imaging, revolutionizing diagnosis and patient care.